*通讯作者

2026

[57] B Wang#, F Hu#, M Chen, Z Xie, S Liu, J Li, D Ding, J Xu, L Pan*

Multi-Channel Automated Programmable Liquid Exchange System Enables High-Quality Sample Preparation for Super-Resolution Microscopy

The Innovation, 2026, 7：101361 (IF:25.7)♥

The Innovation推文链接：https://mp.weixin.qq.com/s/VTKqHYEgMnnftCNzfxHceg

[56] F Xing#, J Yang#, F Hu#, Z Xie, M Chen, M Yang, S Liu, D Ding, L Pan*, J Xu

Super-resolution microscopy reveals nanoscale arrangement of PD-L1 immune checkpoint

Chemical & Biomedical Imaging, 2026, 4: 381-393 (IF:5.7)

南开大学物理学院新闻链接：https://physics.nankai.edu.cn/2026/0326/c575a591549/page.htm

[55] Z Xie, F Hu*, Mn Chen, B Wang, J Li, S Liu, D Ding, I Lee, W Yin*, L Pan*

Quantitative Characterization of Microtubule Ultrastructure Based on Single-Molecule Localization Microscopy.

Cytoskeleton, 2025, in press(IF:2.4)

[54] Ya Ding, Wenting He, Kunhao Wang, Fudong Xue, Ke Zheng, Shiqun Zhao, Dong Qi, Tianyi Li, Peng Xia, Leiting Pan, Liangyi Chen, Zhixing Chen, Lin Yuan, Pingyong Xu

A highly photostable monomeric red fluorescent protein for dual-color 3D STED and time-lapse 3D SIM imaging.

Nature Methods, 2026, 23: 143–152 (IF:32.1)（超分辨成像合作文章）

2025

[53] M Hou, J Yang, M Yang, F Hu, R Zhao, Y Pan, W Li, M Chen, J Xu, K Xu*, L Pan*

Fast and robust drift correction for single-molecule localization microscopy.

Nature Communications, 2025, 16:9031(IF:15.7)♥

南开大学新闻链接：https://news.nankai.edu.cn/ywsd/system/2025/10/13/030069096.shtml

BioArt推介链接：https://mp.weixin.qq.com/s/1Yv_tg7VNmaGft6mnqgWjA

[52] 胡芬, 王波, 解钊, 黎继强, 陈明鑫, 刘帅, 杨建宇, 李任植, 潘雷霆*

单分子定位超分辨成像全链条解决方案

现代仪器与医疗, 2025, 31(4): 45-57

2024

[51] H Dong, F Hu, X Ma, J Yang, L Pan*, J Xu

Collective cell radial ordered migration in spatial confinement.

Advanced Science, 2024, 11: 2307487 (IF:14.1)♥

新闻链接: 南开大学 https://news.nankai.edu.cn/ywsd/system/2024/04/16/030060987.shtml

[50]  J Yang#, Fn Xing#, F Hu, M Hou, H Dong, J Cheng, W Li, R Yan, J Xu, K Xu*, L Pan*

Super-resolution microscopy unveils the nanoscale organization and self-limiting clustering of CD47 in human erythrocytes

Journal of Molecular Cell Biology, 2024, 16: mjae041 (IF:5.9)

新闻链接:  https://physics.nankai.edu.cn/_t12/2025/0425/c571a568630/page.htm

[49]  H Dong, Y Zhou, X Ma, J Liu, F Xing, J Yang, Q Sun, Q Hu, F Hu*, L Pan*, J Xu

Geometric regulation of collective cell tangential ordering migration.

Journal of Innovative Optical Health Sciences, 2024, 17: 2450001 (IF:2.5)

[48]  X Ma#, H Zhang#, S Deng#, Q Sun, Q Hu, Y Pan, F Hu, I Lee, F Xing*, L Pan*

Single-cell manipulation by two-dimension micropatterning.（Review Paper）

Journal of Innovative Optical Health Sciences, 2024, 17: 2330011(IF:2.5)

[47] 邓师禹，胡芬*，侯梦迪，杨建宇，李任植，潘雷霆*

二抗物种特异性对双色STORM成像的影响. (特邀论文)

激光与光电子学进展，2024, 61: 0618008

[46] 侯梦迪, 胡芬*, 杨建宇, 董浩，潘雷霆*

核孔复合物单分子定位超分辨图像的筛选和重构.

中国激光，2024, 51: 0307106

2023

[45] Weisong Zhao, Xiaoshuai Huang, Jianyu Yang, Liying Qu, Guohua Qiu, Yue Zhao, Xinwei Wang, Deer Su, Xumin Ding, Heng Mao, Yaming Jiu, Ying Hu, Jiubin Tan, Shiqun Zhao*, Leiting Pan*, Liangyi Chen*, Haoyu Li*

Quantitatively mapping local quality of superresolution microscopy by rolling Fourier ring correlation..

Light: Science & Applications, 2023, 12: 298 (IF:23.4)♥

新闻链接:  https://www.nsfc.gov.cn/publish/portal0/tab1358/info91503.htm

[44] F Xing, H Dong, J Yang, C Fan, M Hou, P Zhang, F Hu, J Zhou, L Chen, L Pan*, J Xu

Mesenchymal migration on adhesive-nonadhesive alternate surfaces in macrophages.

Advanced Science, 2023, 10: 2301337 (IF:14.1)(封底文章Back Cover)♥

新闻链接: 南开大学 https://news.nankai.edu.cn/ywsd/system/2023/08/19/030057480.shtml

[43]  M Hou, F Xing, J Yang, F Hu, L Pan*, J Xu

Molecular Resolution Mapping of Erythrocyte Cytoskeleton by Ultrastructure Expansion Single-Molecule Localization Microscopy (U-ExSMLM).

Small Methods, 2023, 7: 2201243 (IF:9.1)♥

新闻链接: 南开大学 http://news.nankai.edu.cn/ywsd/system/2023/02/06/030054350.shtml
Wiley MaterialsViews中国  https://mp.weixin.qq.com/s/2zayH9t6vdH_8ykYSrUYbQ

[42]  F Xing, H Zhang, M Li, H Dong, X Ma, S Deng, F Hu, I Lee, L Pan*, J Xu

Regulation of actin cytoskeleton via photolithographic micropatterning.

Journal of Innovative Optical Health Sciences, 2023, 16: 2244005 (IF:2.5)（封面文章）

[41] 杨建宇，胡芬，邢福临，董浩，侯梦迪，李任植， 潘雷霆*, 许京军

结合多次DBSCAN和层次聚类算法的膜蛋白单分子定位超分辨图像分割. (特邀论文)

中国激光，2023, 50: 0307106

[40] 杨建宇，胡芬*，侯梦迪，董浩，陈靖， 潘雷霆*

人红细胞膜骨架超分辨图像的Voronoï分析.

中国激光，2023, 50: 1507104

2022

[39]  F Hu, D Zhu, H Dong, P Zhang, F Xing, W Li, R Yan, J Zhou, K Xu, L Pan*, J Xu

Super-resolution microscopy reveals nanoscale architecture and regulation of podosome clusters in primary macrophages.

iScience, 2022, 25: 105514 (IF:4.1) ♥

新闻链接：https://physics.nankai.edu.cn/2022/1121/c571a497161/page.htm

[38]  Qian Luo, Qiangqiang Liu, Hongcheng Cheng, Jiale Wang, Tian Zhao, Jiaojiao Zhang, Chenglong Mu, Yuanyuan Meng, Linbo Chen, Changqian Zhou, Hong Lei, Jianyu Yang, Guo Chen, Yanjun Li, Leiting Pan, Quan Chen*, Yushan Zhu*

Nondegradable ubiquitinated ATG9A organizes Golgi integrity and dynamics upon stresses.

 Cell Reports, 2022, 40: 111195 (IF:6.9) (超分辨成像合作工作)

2021

[37]  杨建宇, 董浩, 邢福临, 胡芬, 潘雷霆*, 许京军

单分子定位超分辨成像技术进展及应用.

激光与光电子学进展, 2021, 58: 1200001 (ESCI,邀请封面综述文章)

http://www.opticsjournal.net/Articles/Abstract/lop/58/12/1200001.cshtml  下载链接

2020

[36] F Xing, S Qu, J Liu, J Yang, F Hu, I Drevenšek-Olenik, L Pan*, J Xu.

Intercellular bridge mediates Ca2+ signals between micropatterned cells via IP3 and Ca2+ diffusion.

Biophysical Journal, 2020, 118: 1196-1204 (IF:3.1) PDF-8

[35]  胡芬, 林洋, 侯梦迪, 胡浩丰*, 潘雷霆*, 刘铁根, 许京军

基于深度学习的细胞骨架图像超分辨重建.

光学学报, 2020, 40: 2410001（EI，ESCI） 

[34] Shuo Liu, Haobin Wang, Jun Li, Jianhui Zhang, Jian Wu, Yi Li, Yongjun Piao, Leiting Pan, Rong Xiang*, Shijing Yue*

FZR1 as a novel biomarker for breast cancer neoadjuvant chemotherapy prediction.

Cell Death & Disease, 2020, 11: 804 (IF:7.7) (超分辨成像合作工作)

2019

[33] L Pan, P Zhang, F Hu, R Yan, M He, W Li, J Xu, K Xu*.

Hypotonic stress induces fast, reversible degradation of the vimentin cytoskeleton via intracellular calcium release.

Advanced Science, 2019, 6: 1900865 PDF-7 （封底文章Back Cover）（IF:14.1）♥

[32] F Hu, D Zhu, W Pei, I Lee, X Zhang, L Pan*, J Xu.

Rhein inhibits ATP-triggered inflammatory responses in rheumatoid rat fibroblast-like synoviocytes.

International Immunopharmacology, 2019, 75: 105780 (IF:4.7)

[31] F Xing, S Xun, Y Zhu, F Hu, I Drevenšek-Olenik, X Zhang, L Pan*, J Xu.

Microfluidic assemblies designed for assessment of drug effects on deformability of human erythrocytes.

Biochem. Biophys. Res. Commun., 2019,512:303-309 (IF:3.1)  PDF-6

[30] Fulin Xing, Fen Hu, Jianyu Yang, Leiting Pan*, Jingjun Xu.

Structural and functional studies of erythrocyte membrane-skeleton by single-cell and single-molecule techniques.

Journal of Innovative Optical Health Sciences, 2019, 12:1830004 (Invited Review) PDF-5

[29] F Hu, Y Zhao, Z Hui, F Xing, J Yang, I Lee, X Zhang, L Pan*, J Xu.

Regulation of intracellular Ca2+/CaMKII signaling by TRPV4 membrane translocation during osteoblastic differentiation.

Biophysics Reports, 2019, 5(5): 254-263

2018

[28] L Pan, R Yan, W Li, K Xu*.

Super-Resolution Microscopy Reveals the Native Ultrastructure of the Erythrocyte Cytoskeleton.

Cell Reports, 2018, 22: 1151-1158 (IF:6.9)♥  PDF-4

[27] F Xing, P Zhang, P Jiang, Z Chen, J Yang, F Hu, I Drevenšek-Olenik, X Zhang, L Pan*, J Xu*.

Characteristics of Intercellular Calcium Waves Communication in Micropatterned Assemblies of Single Cells.

ACS Applied Materials & Interfaces, 2018, 10: 2937-2945. (IF:9.5)♥ PDF-3

[26] 蒋鹏翀，魏巍，胡芬，张心正，潘雷霆*.

基于激光消融技术的斑马鱼条纹再生的研究.

中国激光，2018, 45(2):0207024（EI）（特邀论文）[Link]

2017

[25] P Jiang, F Xing, B Guo, J Yang, Z Li, W Wei, F Hu, I Lee, X Zhang, L Pan*, J Xu.

Nucleotide transmitters ATP and ADP mediate intercellular calcium wave communication via P2Y12/13 receptors among BV-2 microglia.

PLoS ONE, 2017, 12(8):e0183114 (IF:3.7) [Link]

[24] C Li, Z Li, S Xun, P Jiang, R Yan, M Chen, F Hu, R A Rupp, X Zhang, L Pan*, J Xu.

Protection of the biconcave profile of human erythrocytes against osmotic damage by ultraviolet-A irradiation through membrane-cytoskeleton enhancement.

Cell Death Discovery,2017,3: 17040 (IF:7.0) ♥  [Link]

[23] F Hu, Z Hui, W Wei, J Yang, Z Chen, B Guo, F Xing, X Zhang, L Pan*, J Xu.

Hypotonic stress promotes ATP release, reactive oxygen species production and cell proliferation via TRPV4 activation in rheumatoid arthritis rat synovial fibroblasts.

Biochem. Biophys. Res. Commun.,2017, 486(1):108-115 [Link]

[22] 潘雷霆, 胡芬, 张心正, 许京军*.

多色单分子定位超分辨显微成像术的研究. (综述)

光学学报，2017, 37(3): 0318010 (EI) PDF-2

[21] 杨建宇，潘雷霆*，胡芬，张心正, 许京军.

随机光学重构显微术及其应用研究进展.  (邀请综述)

红外与激光工程，2017, 46: 1103008 (EI) PDF-1

2016

[20] C Li, X Shi, M Chen, X Su, P Jiang,L Pan*.

Ultraviolet light A irradiation induces immunosuppression associated with the generation of reactive oxygen species in human neutrophils.

Journal of Innovative Optical Health Sciences,2016,9(4): 1650001  [Link]

2015

[19] F Hu, F Xing, G Zhu, C Li, J Qu, I Lee, L Pan*.

Rhein antagonizes P2X7 receptor in rat peritoneal macrophages.

Scientific Reports,2015,5: 14012 (IF:4.6) [Link]

2014

[18] F Xing, G Meng, Q Zhang, L Pan, P Wang, Z Liu*, W Jiang, Y Chen, J Tian*.

Ultrasensitive Flow Sensing of a Single Cell Using Graphene-Based Optical Sensors.

Nano Letters,2014,14(6): 3563-3569 (IF:12.262) (微流控芯片合作工作) [Link]

[17] F Hu, L Pan*, K Zhang, F Xing, X Wang, I Lee, X Zhang, J Xu.

Elevation of extracellular Ca2+ induces store-operated calcium entry via calcium-sensing receptors: a pathway contributes to the proliferation of osteoblasts.

PLoS ONE, 2014, 9(9): e107217  [Link]

[16] S Zhu, Y Wang, L Pan*, S Yang, Y Sun, X Wang, F Hu*.

Involvement of transient receptor potential melastatin-8 (TRPM8) in menthol-induced calcium entry, ROS production and cell death in rheumatoid arthritis rat synovial fibroblasts.

European Journal of Pharmacology, 2014, 725(1): 1-9 (IF:5.2) [Link]

[15] G Meng, L Pan*, C Li, F Hu, X Shi, I Lee, I Drevenšek-Olenik, X Zhang, J Xu.

Temperature-induced Labelling of Fluo-3 AM Selectively Yields Brighter Nucleus in Adherent Cells.

Biochem. Biophys. Res. Commun.,2014,443(3): 888-893  [Link]

[14] 吴限，潘雷霆*，刘颖，邢梦溪，张心正，许京军.

多途径介导的小胶质细胞间钙波传递.

生物化学与生物物理进展，2014, 41(2): 179-184  [Link]

2013

[13] L Pan, K Song, F Hu, W Sun, I Lee.

Nitric oxide induces apoptosis associated with TRPV1 channel-mediated Ca2+ entry via S-nitrosylation in osteoblasts.

European Journal of Pharmacology,2013,715(1):280-285  [Link]

[12] X Wu, L Pan*, Y Liu, P Jiang, I Lee, I Drevensek-Olenik, X Zhang, J Xu.

Cell–cell communication induces random spikes of spontaneous calcium oscillations in multi-BV-2 microglial cells.

Biochem. Biophys. Res. Commun.,2013,431(4):664-669  [Link]

2012

[11] L Pan*, X Wang, S Yang, X Wu, I Lee, X Zhang, R A Rupp, J Xu.

Ultraviolet irradiation-dependent fluorescence enhancement of hemoglobin catalyzed by reactive oxygen species.

PLoS ONE, 2012, 7(8): e44142  [Link]

[10] Ting-Hsuan Chen, Xiaolu Zhu#,Leiting Pan#, Xingjuan Zeng, Alan Garfinkel, Yin Tintut, Linda L. Demer, Xin Zhao and Chih-Ming Ho. (#Contributed Equally)

Directing Tissue morphogenesis via Self-Assembly of Vascular Mesenchymal Cells.

Biomaterials, 2012, 33(35): 9019-9026 (IF:15.3) [Link]

2011

[9] Songzi Kou, Leiting Pan*, Danny van Noort, Guixian Meng, Xian Wu, Haiying Sun, Jingjun Xu, Imshik Lee.

A multishear microfluidic device for quantitative analysis of calcium dynamics in osteoblasts.

Biochem. Biophys. Res. Commun.,2011,408(2):350-355 [Link]

[8] L Pan*, X Wu, D Zhao, N Ma’ani Hessari, I Lee, X Zhang, J Xu.

Sulfhydryl Modification Induces Calcium Entry through IP3-sensitive Store-operated Pathway in Activation-dependent Human Neutrophils.

PLoS ONE, 2011, 6(10):e25262 [Link]

2010

[7] X Wu, L Pan*, Z Wang, X Liu, D Zhao, X Zhang, R A Rupp, J Xu.

Ultraviolet irradiation induces autofluorescence enhancement via production of reactive oxygen species and photodecomposition in erythrocytes.

Biochem. Biophys. Res. Commun., 2010, 396(4): 999-1005 [Link]

[6] W Sun, L Pan, Z Ma*.

Hypo-osmotic stress enhances the uptake of polyethylenimine/oligonucleotides complexes in A549 cells via Ca2+ mobilization from intracellular stores.

Oligonucleotides, 2010, 20(2): 111-115

[5] X Zhang, X Liu, Lg Pan, I Lee*. [Link]

Magnetic Fields at Extremely Low-Frequency (50 Hz, 0.8 mT) Can Induce the Uptake of Intracellular Calcium Levels in Osteoblasts.

Biochem. Biophys. Res. Commun., 2010, 396(3): 662-666

2009

[4] L Pan,X Zhang, K Song, W Cai, X Wu, R A Rupp, J Xu*.

Real-time imaging of autofluorescence NAD(P)H in single human neutrophils. 

Applied Optics, 2009, 48(6): 1042-1046 [Link]

[3] 潘雷霆,孙文武,齐继伟,吴限,宋昆,胡芬,张心正,许京军*.

佛波酯诱导大鼠滑膜细胞骨架改变的研究. 

生物化学与生物物理进展，2009, 36(1): 83-87 [Link]

[2] X Zhang, J Wang, B Tang, X Tan, R A Rupp, L Pan, Y Kong, Q Sun, J Xu*.

Optical trapping and manipulation of metallic micro/nanoparticles via photorefractive crystals.

Optics Express, 2009, 17(12): 9981-9988 [Link]

2008

[1] L Pan, X Zhang, K Song, X Wu, J Xu*.

Exogenous nitric oxide-induced release of calcium from intracellular IP3 stores via S-nitrosylation in respiratory burst-dependent neutrophils.

Biochem. Biophys. Res. Commun., 2008, 377(4): 1320-1325 [Link]